pentobarbital will decrease the level or outcome of etravirine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.pentobarbital will reduce the level or influence of tofacitinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Lack of, or reduced response to tofacitinib may well arise when coad